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Voss MH, Hussain A, Vogelzang N, Lee JL, Keam B, Rha SY, et al

Since it is well known that GSH depletion leads to the upregulation of antioxidant genes, many of which are under Nrf2 control and, that in several types of tumors, Nrf2 is constitutively activated [122, 123], a new and indirect approach for cancer therapy may be used to modulate the Nrf2-ARE pathway

Wen CP, Lee JH,Tai YP, et al

Reasons for inhaled GSH's effectiveness include its role as a potent antioxidant, and possibly improved oxygenation and host defenses

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