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For patients with high cardiovascular risk, additional options include PCSK9 inhibitors and newer agents such as inclisiran (NICE TA733) and bempedoic acid (NICE TA694)

However, rtPA therapy can dramatically enhance the risk of hemorrhagic conversion and BBB permeability

In summary, ketone bodies inhibit cardiomyocyte proliferation after birth, possibly by regulating lipid metabolism in the neonatal heart

Organized fiber architecture directly correlates with higher tensile strength and reduced re-injury risk at the repair site