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Psychiatry 73, 774781

Each component is associated in published literature with a distinct mechanistic pathway: copper-dependent ECM-related signaling (GHK-Cu), inflammatory pathway modulation (KPV), angiogenesis pathway markers (BPC-157), and actin-driven cell-migration assays (TB-500)

2018 Jan Anup Sharma, Patricia Gerbarg, Teodoro Bottiglieri, Lila Massoumi, Linda L Carpenter, Helen Lavretsky, Philip R Muskin, Richard P Brown, David Mischoulon

Core functions of skeletal cells Osteoblast: Derived from bone marrow mesenchymal stem cells, responsible for synthesizing bone matrix (type I collagen, osteocalcin, bone alkaline phosphatase), promoting calcium and phosphorus deposition, and constructing new bone, it is the core driving force of bone formation