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Cell Death Dis 5:e1179

These analogs are beneficial to diabetes patients in numerous ways as they work by enhancing glucose-dependent insulin secretion, suppressing elevated glucagon secretion, slowing gastric emptying, and suppressing appetite

GLP-1 is an insulinotropic glucoincretin hormone, known to promote -cell survival via G protein-coupled receptor 40 and increase beta cell proliferation through TCF7l2/Wnt pathway 41,42,43

Think of it like noise-canceling headphones that slowly stop noticing the drone of an airplane engine

(2015, May 1)

It requires weight-based dosing and IV or SubQ administration under clinical supervision