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Comparison of whole-blood glutathione peroxidase activity, levels of serum selenium, and lipid peroxidation in subjects from the Fishing and Rural Communities of Rabo de Peixe village, San Miguel Island, the Azores Archipelago, Portugal

Similarly, ovarian oxidative stress model mice exhibit inhibition of the Nrf2/HO-1/GPX4 pathway (Niu et al., 2023), suggesting that GPX4 deficiency-induced ferroptosis may contribute to reduced ovarian reserve

This is a significant phenotype, as a similar reduction in circulating triglycerides was not observed with a liver-specific loss of critical lipogenic enzymes, such as fatty acid synthase (FASN) 81

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Statistical analyses The kappa coefficient was calculated to assess the level of agreement for the quality scores between the two coders [57]

10.4081/aiua.2015.3.190 [DOI] [PubMed] [Google Scholar] Kritis A