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It is postulated that ADHD may result from deficits in the dopaminergic system in cortical brain structures such as the prefrontal cortex, subcortical areas such as striatum [54, 55]

Microneedling, a technique that creates controlled micro-injuries in the scar tissue, stimulates the body's natural healing response and can improve both texture and pigmentation

The addition of prebiotics like Inulin helps feed beneficial gut bacteria

While the first studies showing this were in mice [14], human studies have corroborated these findings [200], although its importance in relationship to traditional clearance pathways across the BBB and subarachnoidal granulations has been challenging to quantify

2.10.2 Data analysis and data processing The sequences obtained were analyzed using the bioinformatics platform QIIME2 version 2020.6