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In lupus prone MPL/lpr mice, administration of bortezomib was found effective in preventing and more importantly treating established disease ( Although proteasome inhibition is attractive, the main concern for adding these seemingly potent medications in the SLE therapeutic armamentarium remains the severe toxicity associated with their chronic use

Keith Lafferty MD, Fort Myers on June 29, 2025

are used as biocontrol agents to outcompete aflatoxigenic strains and inhibit their dominance, hence preventing the generation of aflatoxins (Daou et al

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