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The recognised conditions are type 2 diabetes, prediabetes, high blood pressure, high cholesterol or dyslipidaemia (an unhealthy balance of fats in the blood), cardiovascular disease, and obstructive sleep apnoea 1,2

Rahemi et al., 2023)

Figure 2 Differential Gene Expression (DGE) was performed, and subsequent Gene Set Enrichment Analysis (GSEA) was executed on DGE results to better understand pathway enrichment discrepancies between sample types

AMG133 was administered in longer treatment intervals with either monthly or less frequent dosing

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