Yes, especially for people who dont absorb B12 well due to digestive issues, genetic variations (like MTHFR), or medications such as metformin or acid blockers
(PubMed) What people claim it does fat loss lean mass gain sleep improvement recovery What the science supports (and what it doesnt) Supported with more confidence: These agents can stimulate GH signaling (and in CJC-1295s case, IGF-1 rises in human data)
At Perfect B in Doral, FL, CJC-1295/Ipamorelin is prescribed as part of a supervised peptide protocol because the clinical difference between starting at 37 versus waiting until 52 is measurable and significant
Theres not strong evidence supporting systemic regeneration claims as presented online, especially when combining with other experimental peptides
Hydroxocobalamin is the preferred agent in this patient population (see separate monograph in Less Common Drugs)
Though not FDA-approved for weight loss, it is used off-label to reduce stubborn fat