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Diabetes 2001, 50, 2815-2821, doi:10.2337/diabetes.50.12.2815

Sattar N, McConnachie A, Shaper AG et al

Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66