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You turn to Reddit for self-tanner recommendations, and discover something called the "Barbie Drug," or more technically, Melanotan II

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Strong CYP3A inhibitors (such as ketoconazole, itraconazole, and ritonavir) would be expected to increase orforglipron exposure, potentially necessitating dose adjustment

In seriously ill patients it may be advisable to administer both vitamin B12 and folic acid while awaiting the results of distinguishing laboratory studies

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