In some embodiments, the otoprotectant is a compound of Formula (XI) having the structure of Formula (XIa): In some embodiments, the otoprotectant is any one of the following compounds: or a pharmaceutically acceptable salt, pharmaceutically acceptable solvate or hydrate, pharmaceutically acceptable salt hydrate, or pharmaceutically acceptable prodrug thereof
Glucagon-like peptide-1 (GLP-1) is a hormone produced by the stomach in response to food, which plays an important role in regulating appetite and blood sugar levels
GSK3beta activity modifies the localization and function of presenilin 1
It is characterized by the fact that its double bonds are separated by only one single bond, which is rare in nature
Do the cardiovascular and renal benefits of SGLT2 inhibitors and GLP-1 receptor agonists demonstrated in patients with established CVD extend to lower-risk patients
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