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Heritage and perspectives POMC and its derivatives have been discovered over nearly a century: alpha-MSH identification by Harris in the 1950s, POMC characterization by Nakanishi and Numa (Nature, 1979), cloning of the five MC1R-MC5R receptors between 1992 and 1994 (Cone, Mountjoy, Gantz teams)

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Studies in elderly human populations and aged primates observed measurable changes in nocturnal melatonin levels and circadian melatonin rhythm patterns in subjects receiving the AEDG peptide or epithalamin (6, 7)

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IGF-1 LR3 Nasal Spray Nasal administration of IGF-1 LR3 provides a non-invasive alternative to injections, allowing direct absorption of the peptide through the nasal mucosa