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Order related labs such as: o Complete Blood Count (CBC) o Liver enzymes (AST, ALT, bilirubin) o Kidney function tests (creatinine, eGFR) o Methylmalonic acid (MMA) and homocysteine to check B12 activity

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Management: Rotate injection sites between different areas

119 USP22, a well-known role co-activator of VEGF-A, specifically plays a crucial role by reversing the ubiquitination by ubiquitylating enzymes

Platinum drugs: from Pt(II) compounds, Pt(IV) prodrugs, to Pt nanocrystals/nanoclusters

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