Hypothyroidism is classified as primary or secondary, with primary causes including iodine deficiency, autoimmune diseases (e.g., Hashimotos thyroiditis), enzymatic damage, radiotherapy, thyroid surgery, certain medications, and chronic or infiltrative conditions, while secondary hypothyroidism results from pituitary or hypothalamic disorders
Consult a healthcare professional before use if pregnant, breastfeeding, taking medication or managing a medical condition
Other peptides sometimes used in gut-repair protocols include KPV, a small anti-inflammatory peptide that helps calm the intestinal lining
Best for: MTHFR mutations (C677T, A1298C) Supporting methylation directly Neurological symptoms (brain fog, neuropathy) Depression and mood disorders Elevated homocysteine Advantages: No conversion required immediately bioavailable Directly supports methylation cycle Crosses blood-brain barrier easily Lowers homocysteine effectively Potential downsides: Can cause overmethylation symptoms in sensitive individuals (anxiety, insomnia, irritability) May need to start with very low doses Not ideal for those with histamine issues or overmethylators Typical dosage: 500-5000mcg daily (start low) 2
The free peptide reconstitution calculator makes this math simple
Because glutathione is a peptide (a small protein), the enzymes in your digestive tract, specifically peptidases , often recognize it as food rather than a supplement
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