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Prior severe nausea or gastroparesis may favor semaglutide over tirzepatide due to lower initial GI burden

Romero-Haro AA, Figuerola J, Alonso-Alvarez C

The peptide works best as part of a comprehensive approach addressing all aspects of recovery

This could be due to ALCs quick absorption and capacity to cross the blood-brain barrier, potentially altering the gut microbiota composition and limiting the abundance of TMA-producing bacteria

10.1056/NEJMoa2024816 9 HershbergerS