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In this research, the increase of the activity of aminotransferases and alkaline phosphatase due to treatment by thioacetamide implies the liver cells injuries due to thioacetamide because the enzymes are available inside cells and in the event of damaging cells they enter to serum
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It has an exceptionally high (620 L/kg)apparent volume of distribution because most of the drug ends up being in tissues and not in plasma
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GSK-3 also mediates the ubiquitination and degradation of Mcl-1
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