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However, it has been suggested that GLP-1RAs may enhance their anti-inflammatory effects by increasing the number of peripheral Tregs [12, 146]

For those wondering about the differences between semaglutide, tirzepatide, and retatrutide , the data shows a clear hierarchy of efficacy forming among incretin-based therapies

Increased A and neurofibrillary tangle deposition in the brain subsequently promote further cerebrovascular dysfunction via increased ROS production and inflammation (Cheignon et al., 2018)

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Exclusion criteria and differential diagnosis