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Insulin resistance is often a result of excess body fat, particularly around the abdomen

NTZ-elicited hepatoprotective effects are suggested to be mediated via modulation of PERK/CHOP10 signaling along with attenuated proapoptotic oxidative stress and proinflammatory signaling

Tirzepatide, a dual GLP-1 and GIP receptor agonist, has demonstrated superior efficacy for weight reduction and improved metabolic health compared with single GLP-1 agonists

Compounded medications are custom-made by a pharmacy for an individual patient, usually when an FDA-approved drug isn't available or a patient has a specific need (like an allergy to an ingredient in the commercial product)

Plans would also have been at some financial risk if their actual costs for covering GLP-1s were higher than they expected