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KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic rats

Solnier, J., Du, M., Zhang, Y., Roh, Y

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Modern interest in NAD biology was reinvigorated by the 2000 discovery by Imai, Armstrong, Kaeberlein, and Guarente that the silent information regulator 2 (Sir2) family sirtuins are NAD-dependent protein deacylases, establishing a direct link between cellular NAD availability and gene-silencing, metabolic, and aging-related signaling pathways

Mayo B, Vzquez L, Flrez AB