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Dr Frederick explains that good blood sugar control is one of the key mechanisms at work in a fertility diet: "You want to avoid foods that increase insulin resistance - a hormone released into the bloodstream during blood sugar spikes that can disrupt ovulation

As MTHFR polymorphisms-induced MTHFR activity decline is irreversible, clinicians tried to use supplement of folate to help methylation process and change the pathogenesis state

Frantz et al., 2009