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Differentiation of intestinal stem cells and enteroendocrine cells into L-cells The incretin hormone GLP-1 is one of the hormones that is produced by post-translational processing of proglucagon by proprotein convertase subtilisin-kexin type 1 (Pcsk1) or Pcsk3 in L-cells of the distal small bowel and colon

Mast cells release histamine, prostaglandins, and other inflammatory mediators

Eventually, it prompts a more substantial production of the peptide hormone

By week 9, I suddenly felt normal again