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Steroid injections have been used for alopecia areata since 1958

Modig, K., Pfrommer, B

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Clinical indications for intradiscal injection of MSCs are (a) treatment of discogenic pain without severe compression and/or neurologic deficits and (b) treatment of the adjacent degenerated discs during decompressive spinal surgery

Acetaldehyde If theres a single compound that can be blamed for making hangovers feel so unpleasant, its arguably acetaldehyde

This creates localized pressure, increases pain, and can cause the solution to track back along the needle path and leak out