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Weight loss was dosedependent (for example, ~8% at 1 mg), while the placebo group lost around 2%

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doi:10.3390/medicina59040778

Despite lots of big lingering questions, many clinicians dont think it actually matters right now how GLP-1 interacts with brain receptors on a cellular level, says Laura Huckins, PhD, an associate professor of psychiatry at the Yale School of Medicine

RETA again led to significant improvements in body composition that were partially retained after RETA withdrawal despite the dramatic weight rebound in the RETA-w/d group