It should be kept away from strong chelators (such as high levels of EDTA and related sequestrants), reducing sugars, thiol-bearing actives, and high concentrations of direct acids (for example ascorbic acid or alpha-hydroxy acids at low pH), all of which can compete for the copper center or disrupt the peptide-metal bond and shift the characteristic blue color toward brown or colorless degradation products
It is not known if CONTRAVE is safe and effective when taken with other prescription, over-the-counter, or herbal weight-loss products
PubMed pubmed.ncbi.nlm.nih.gov [54] Semaglutide for the treatment of obesity PubMed pubmed.ncbi.nlm.nih.gov [55] Value of GLP-1 receptor agonists versus long-acting insulins for type 2 diabetes patients with and without established cardiovascular or chronic kidney diseases: A model-based cost-effectiveness analysis using real-world data ScienceDirect science/article/abs/pii/S0168822723001006
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(1976) Evaluation of genetic risks of alkylating agents