But their side effect profiles differ dramatically
C max for the ESRD group was outside the pre-specified no effects limits and appeared to be lower than in the other RI groups
Known risks include multiple pregnancies (eg, twins or triplets) and related pregnancy complications, as well as side effects in the female partner when ovulation-inducing drugs are used
Second, fluctuating concentrations may increase side effects during the injection day and rebound hunger during the off-week, creating an unpredictable experience
Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, et al
Under normal physiological conditions, however, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), giving it a fleeting half-life of just a few minutes