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As chronic inflammation and mitochondrial dysfunction can result in oxidative stress (54, 55, 56, 57) and our results show that human inflammatory PE placentas exhibit more oxidative DNA damage (Fig 1I and J), we next investigated whether LPS treatment leads to placental oxidative DNA damage in this model

Measured HbA1c (a three-month blood-sugar marker) and body-weight change

doi: 10.1093/brain/awm038 121 PopescuBFLucchinettiCF

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