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Preclinical and clinical studies demonstrate that co-administration of these peptides achieves superior reductions in bodyweight, appetite, and fasting glucose than either agent aloneachieving up to a 17% reduction in bodyweight in non-diabetic individuals and a 15.6% reduction in patients with type 2 diabetes over 2032 weeks

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Frontiers in Endocrinology, 15, 1431292

The researchers pointed out that sticking to the medication, eating enough protein, and having regular check-ups seemed to lead to better results