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In addition, as a narrative review, we synthesize the existing literature thematically, rather than relying on systematic meta-analysis

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The average annual cost per patient for a GLP-1 drug is $12,000, according to a Peterson-KFF tracker

However, its dose-limiting toxicities, such as hepatotoxicity, limit its therapeutic usefulness

Significant prevalence of lipid disorders, estimated according to the US NCEP-ATP III ( National Cholesterol Education Program Adult Treatment Panel III ) guidelines, was also observed in the nationwide studies LIPIDOGRAM2003, LIPIDOGRAM2004 and LIPIDOGRAM2006, in which a total number of nearly 49,000 primary health care (PHC) patients were eventually included in the databases (including LIPIDOGRAM 2015) [1820]