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They found that when in these animals, on average, the intracellular pigment optical density in SNpc NM + neurons was as high as in PD patients, this was associated with a PD phenotype, including hypokinesia, Lewy body-like formation, and nigrostriatal neurodegeneration

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This regulatory approval highlights the relevance of HTY in dietary contexts, while also emphasizing the importance of dose and formulation [17,18,19]

However, this process is non-selective and influenced by regional differences in receptor density, blood flow, and hormonal sensitivity

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