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Whether these additions provide meaningful benefit is debatable, but some patients report improved energy and reduced side effects with enhanced formulations

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Effects of liraglutide on expressions of lipid metabolism-related genes in rats with T2DM and fatty liver

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Some supplements, such as berberine, fiber, omega-3s, probiotics, and curcumin, may offer mild metabolic support, but they do not work like prescription GLP-1 drugs and should not be presented as substitutes (Reference)

Treatment discontinuation due to side effects occurred in 4.3%, 7.1%, 6.2%, and 2.6% of participants in the 5, 10, 15 mg, and placebo groups, respectively [18]