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10.3402/ejpt.v7.31858 233 KentK

Studies have shown [6] that SIRT4 can inhibit fatty acid oxidation in hepatocytes and muscle cells, therefore, GDH may be involved in lipid metabolism through SIRT4

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Results (Be warned this is a tiny study!) 31 patients were in the study, 21 were women, 19 of them were over 65 years old

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The efficacy and safety of mipomersen have been studied in randomized clinical trials evaluating patients with homozygous familial hypercholesterolemia, heterozygous familial hypercholesterolemia, or severe hypercholesterolemia 113,114,115