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Preclinical studies and clinical trials suggest that antioxidants, such as small thiol molecules (N-acetyl-L-cysteine and carbocysteine), antioxidant enzymes (glutathione peroxidases), activators of Nrf2-regulated antioxidant defense system (sulforaphane), and vitamins, for example, C, E, and D, enhance the endogenous antioxidant system and reduce oxidative stress

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Nature 558 , 529530 (2018)

MD trajectories are available at Source data are provided with this paper

The refusal to provide this essential treatment a day early, when the patient is symptomatic, is fundamentally different from a dietary suggestion

9.2 ) and detailed information on intensification of therapy to meet individualized needs