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Weight loss typically begins within the first few weeks of treatment but follows a gradual trajectory rather than rapid drops

Dong D, Zielke HR, Yeh D, Yang P

Human safety data are limited, and animal studies suggest potential risks

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Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-dihydroxyvitamin D deficiency

Researchers at UC Irvine issue a warning that GLP-1RAs may be dangerous for children Source: UC Irvine School of Medicine Irvine, CA, August 28, 2023 A team of clinicians, exercise scientists, pharmaceutical scholars, ethicists and behavioral experts at the University of California, Irvine, outlined their concerns that the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) to treat childhood obesity and type 2 diabetes may have unintended and adverse consequences for childrens health