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Circulation 2016;133:124963

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GLP-1 receptor activation primarily works through appetite suppression, slowed gastric emptying, and improved glucose metabolism

When we become nutritionally deficient in things, or our body thinks that there is a real deficit of food around it will upregulate our appetite and push us to try and eat more. Medlin advice to patients is to build in healthy habits and routine before beginning to taper off otherwise, as we know from every other fad, a restrictive diet rather than a lifestyle change will always end up with a weight pendulum swinging

10.1016/j.yexcr.2020.112056 55 MilteR.CrottyM