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The introduction of advanced pharmacotherapies, including GLP-1 receptor agonists (GLP-1 RA), dual Glucose-dependent Insulinotropic Polypeptide/Glucagon-like Peptide-1 (GIP/GLP-1) agonists, and emerging triple agonists, has facilitated a shift from weight-centric goals to precision-based obesity care

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HNL: Who should consider taking these drugs

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Clinical trials show highly variable blood pressure responses: some patients experience modest elevation (typically 38 mmHg) during dose escalation, while others see decreases of 510 mmHg