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Despite this distinction, both drugs effectively treat type 2 diabetes

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Berberine (500mg, 2-3 times daily with meals): The most robust research exists for this compound

More recently, a survey conducted in August 2025 found that nearly 12% of Americans had used a GLP-1 drug for weight loss at some point, with GLP-1 sales projected to reach $100 billion by 2030

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