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Moreover, GLP-1 RAs also exert beneficial roles on multiple organ systems in which the GLP-1 receptors exist, including the cardiovascular system

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Wang Y, et al

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2024;31(4):e523e527

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In the SURPASS-2 trial, which compared it head-to-head against semaglutide 1 mg over 40 weeks, tirzepatide lowered HbA1c by about 2.0 to 2.3 percentage points across its 5, 10, and 15 mg doses, versus roughly 1.9 points for semaglutide, with greater weight loss as well

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