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The difference is simply which tissue layer receives the material

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The global prevalence of AD is projected to increase from 57 million to 152 million by 2050, imposing a significant economic burden on society [1]

Sinjari B, Diomede F, Khavinson V, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S

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We describe evidence showing that disturbed glutathione homeostasis may be responsible for the lack of fever during infections