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Although the precise mechanisms of IL-6-associated IR is not well characterized, human adipocytes from IR individuals were shown to exhibit significantly higher IL-6 expression levels [45]

Boomsma D, Busjahn A, Peltonen L

This doesnt change the effectiveness of the treatment itself, but it can affect the perceived timeline

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muciniphila treatment, the neurofunctional score and foot fault were significantly better in the A