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The results of drug release experiments showed that the MNs/GLP-1RAs@NPs-WYRGRL could release approximately 92% of GLP-1RAs@NPs-WYRGRL within 2 h post-administration (Fig

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& Sacks, S

For example, in both NCI-716 and STC-1 cells, berberine, a natural bitter plant alkaloid commonly used as an antibiotic, was shown to dose-dependently stimulate GLP-1 secretion via T2R38 ( 2 , protein kinase C and/or phosphodiesterase, attenuates GLP-1 secretion induced by bitter tastants (59)