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TGF Beta value was significantly higher in the RAD group compared to the control group ( p 0.0001), and a significant decrease was observed in the RAD+LCAR and LCAR groups compared to the RAD group ( p 0.0001, for both) (Fig

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In peripheral neuropathic pain, Res inhibits neuroinflammation, activates AMPK, regulates voltage-gated sodium (Nav) 1.7 and potassium channels, and interacts with the serotonergic system 25