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481 Elevated serum NAMPT, together with inflammatory factors, such as IL-6, IL-8 and TNF-a, is associated with an increased likelihood of exhibiting NAFLD and NASH

78 mTORC1 participates in protein, glucose and lipid metabolism mainly through phosphorylation and activation of p70S6 kinase 1 (S6K1), while mTORC2, an effector of PI3K, contributes to the activation of Akt

(JAMA Network) Whats Next for Tirzepatide Research

BPC-157 offers protective benefits against NSAID toxicity and related adverse side effects

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In conclusion, while GLP-1RAs and GLP-1/GIP dual agonists offer significant clinical advantages, ongoing research and vigilant monitoring of their adverse effects and safety are essential for optimizing their therapeutic application