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I certainly don't," Russell Wesdyk, associate director for Regulatory Affairs at the FDA's Center for Drug Evaluation and Research, said during the hearing

The two most researched mutations are C677T and A1298C

Also, it must be remembered that certain medications/supplements may have more or less of an impact on different people depending on individual factors such as genetics and other medical problems that they might have

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10.1007/s13361-013-0822-7 [DOI] [PubMed] [Google Scholar] 69.Busso N, Wagtmann N, Herling C, Chobaz-Peclat V, Bischof-Delaloye A, So A, et al