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The headline adjusted meta-regression coefficient (0.6 nmol/L/year) is inflated by the random-effects weighting scheme and is not a biological rate

This H-bonding network in canonical PDOs prevents the active-site water molecule from participating in the oxidation of the persulfide product, leading only to the formation of an RSSO 2 - intermediate, which is then hydrolyzed by an external water molecule to release sulfite 40

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Mnchberg et al., 2007

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