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Drmic et al., Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine, World J

Prior to the synthesis and isolation of these peptides, research into accelerated tissue healing and recovery relied largely on broad growth factors and nonspecific interventions

The two peptides use complementary rather than identical mechanisms

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In rodent models, behavioral hyperactivity, stereotypy (repetitive non-functional movements), hyperthermia, and muscle rigidity are the primary indicators

The practical effect of longer duration is that trials can measure outcomes over weekly and multi week windows with consistent exposure, rather than focusing only on short time course endpoints