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N Engl J Med (2006) 355(16):1699713.10.1056/NEJMra043632 21 AbrahamELaterrePFGarbinoJPingletonSButlerTDugernierTet alLenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients

Histologically, ephelides have fewer melanocytes but have more melanosomes, which are larger in size

doi: 10.1161/ATVBAHA.111.229765

In this narrative review, we summarize and discuss current evidence on the bidirectional relationship between MASLD and T2DM, focusing on epidemiological data, pathophysiological mechanisms, clinical implications, and pharmacologic treatments