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In the recent European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO) clinical practice guidelines on the management of MASLD it was also stated that PIO can be used safely in individuals with non-cirrhotic MASH [6]

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However, as reported concentrations of GSH are in the range of 0.2 mol/l in CSF and 1 mmol/l in brain tissue, 7 GSH in CSF would not appreciably change the MRS determination of GSH in brain tissue

[DOI] [PMC free article] [PubMed] [Google Scholar] (72).Do DP, Pai SB, Rizvi SA, D'Souza MJ

The role of the inflammasome in heart failure