Olfactory and taste receptors are not just in the nose and tongue, but everywhere in the body including the lungs, the vasculature, the gut, brain, heart and kidneys
These breakthrough findings not only confirm at the molecular level the molecular targets through which GLP-1RAs improve neurodegenerative diseases by regulating glucose-lipid metabolism pathways, but also further establish a theoretical framework for the synergistic regulation of metabolic intervention and neuroprotection (Figure 5)
As orthopaedic surgeons, we must take a holistic approach to patient care, considering comorbidities and medications to optimize surgical outcomes
Usually, the "cocktail" contains a mixture of magnesium, calcium, B vitamins, and vitamin C
"Before we had no way of predicting who would benefit from therapies
The primary endpoint of the FLOW study is a renal composite measure of a persistent eGFR decline 50% from the start of the trial, end-stage renal disease, death from renal disease, or death from CVD [58]