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PEMT (liver/cells): This gene impacts your bodys ability to make phosphatidylcholine, a vital compound needed for cell membranes, brain development, bile flow from the liver, and muscle health

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However, cytochrome P450 (CYP) enzymes, including CYP2E1, CYP1A2, and CYP3A4, convert 59% of acetaminophen to a highly reactive metabolite, N-acetyl- p -benzoquinonimine (NAPQI) (Corcoran et al